U225

Intradermal Injection Device
for Aesthetic and Dermatological Applications -
PRP/PRF Injections, Mesotherapy and Meso-Botox

U225 | לי דניאלס

Indications and Applications

The U225 intradermal injection device is widely used in Israeli clinics. It delivers safe, precise and effective treatments.

Indications include:
1. PRP/PRGF/CGF/PRF injection into the scalp, face or body.

2. Treatment of fine lines and wrinkles, including delicate areas around the eyes and lip lines.

3. Treatment of cellulite and localized fat.

U225 - תצוגת מוצר | לי דניאלס

U225 Features

Manual injection control

High injection frequency for rapid, uniform coverage

Precision: injection depth is adjustable from 1 to 10 mm

Ultra-fine needle to minimize pain

Improved patient satisfaction​

U225 | לי דניאלס

Advantages of the Electro-Pneumatic Technology

The U225 is an electro-pneumatic device, air-driven rather than motorized. Both the extrusion pressure that delivers the product and the pressure that drives needle penetration are powered by compressed air. This approach significantly reduces pain and skin trauma while improving results.<br>The compressed air is supplied by a dedicated, portable compressor. The compressor is light and compact, operating quietly and reliably.

תצוגת מוצר | לי דניאלס


The Advantages of the U225 for Your Clinic

01

Reduced Pain

The U225 is barely felt during treatment and significantly reduces needle-puncture trauma and bruising

02

Speed and Comfort

Improves treatment outcomes and enhances ergonomic comfort for the practitioner

03

Improved Results

Performing a large number of pain-free punctures leads to a significant improvement in treatment outcomes, including the treatment of scars, hair thinning and fine lines.

Watch the U225 Operating Tutorial

How the U225 Mesogun Works — Controlled Depth, Dose and Precision

The U225, manufactured by Needle Concept of France and distributed in Israel by Lee Daniels, is a mesotherapy gun (Mesogun) built on electro-pneumatic technology — injection powered by controlled compressed air, air-driven rather than motorized. Unlike manual injection, where depth and product volume vary from puncture to puncture, the U225 delivers a series of uniform micro-injections — each at an identical depth and dose.

Three parameters can be precisely controlled by the practitioner:

  • Penetration depth: fine adjustment from 1 to 10 mm, to match delicate areas (around the eyes, neck) with deeper areas (scalp, body).
  • Dose per puncture: the product volume of each micro-injection is preset, so an identical amount reaches every point.
  • High injection frequency: a high injection rate that enables fast, uniform coverage of a large treatment area while keeping the patient comfortable.

Using compressed air for both needle penetration and product delivery reduces skin trauma and the sensation of pain, producing a consistent, reproducible result from treatment to treatment and from practitioner to practitioner.

Clinical Applications of the U225

  • Mesotherapy: injection of cocktails of vitamins, minerals, hyaluronic acid and active ingredients into the skin layers, to revitalize and nourish the skin.
  • PRP and PRF: uniform injection of autologous plasma into the scalp, face and body, with precise distribution and reduced pain.
  • Polynucleotide-based protocols: the U225 is a versatile intradermal injector, also well suited to the systematic delivery of polynucleotide preparations.
  • Hair and scalp treatments: an area where a large number of precise, pain-free punctures is a significant advantage.

Frequently Asked Questions — U225

What is the U225 used for?

The U225 is a mesotherapy gun (Mesogun) for intradermal injections. It is suited to mesotherapy, PRP/PRF injections and hair, face and body treatments, and is also used for polynucleotide protocols — via precise micro-injections at controlled depth and dose.

What is the difference between manual injection and a mesogun?

With manual injection, needle depth and product volume vary from puncture to puncture and depend on the practitioner’s skill. With the U225 mesogun, every micro-injection is performed at a fixed depth and dose and at a rapid pace, improving the uniformity of the result and reducing pain and skin trauma.

At what depth can you inject with the U225?

The injection depth can be adjusted from 1 to 10 mm, depending on the treatment area and the type of product being injected.

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